Players represent alien races that are seeking to spread themselves onto five foreign worlds. To accomplish this, they make challenges against other players and enlist the aid of interested parties. But alien powers, which are unique to each race, give players ways to bend or outright break some rule in the game.

This is an updated version of the original Eon Cosmic Encounter (1977).

Major differences between this version and the Eon version:

Flares in the Mayfair version are "use once and discard", as opposed to Eon's version, which lets players keep them in their hands and reuse them.
Mayfair introduced phase / timing icons on all Powers, Flares, and Edicts to clearly indicate when each could be used.
Mayfair introduced new Edicts, and several new Alien Powers with corresponding Flares.
Moons (in the More Cosmic Encounter expansion) have text written on their backs (instead of only a number which you used to refer to a separate list). Moons were also divided into four categories: Full Moons have a major effect on the game; Half Moons are more moderate in their effects; Quarter Moons have a minor effect; Cheese Moons introduce silliness to the game.
Lucre (also in the More Cosmic Encounter expansion) was revamped with additional uses, and players were required to spend it to affect their challenge totals.
Mayfair introduced a new card: Reinforcements (also in the More Cosmic Encounter expansion).

Expanded by:

More Cosmic Encounter
Cosmic Supreme (allows 2 more players)

Re-implements:

Eon's Cosmic Encounter (1977)

Re-implemented by:

Simply Cosmic, Mayfair's simplified version (which can be added to allow 4 more players)

Danmaku!!